The significant advantages are:

• After transfection and selection resulting cells show a better long term stability of expression
• Better yield of stable expressing cells
• Higher middle expression level of resistant cells. Consequently it is possible to isolate more cell clones with high expression level

Our proprietary IGAMI technology uses special stabilizing and enhancing sequences. These sequences integrate together with the transgene into the host chromatin and prevent gene silencing of the neighbouring transgene. The resulting cell lines show an increased recombinant protein expression and a better long term expression stability

Using our IGAMI technology a fast and easy stable cell line generation is possible.